Total Synthesis Ltd

Connecting The Dots In Your Synthesis Workflow

Through Catalysis & Beyond

Services

01

Catalysis & Fine Chemicals Manufacturing

The catalysis arm of the company’s operation has assisted in the development and scale-up of several highly reactive and widely used catalysts, both transition-metal based and organocatalysts. This includes the PEPPSI family of organopalladium catalysts developed in the academic research laboratories of Professor Michael G. Organ at York University in Toronto. Custom catalyst preparation is a specialty and requests for preparations can be made from the contact link above. TSL has provided high-quality chemicals up to 500 grams for over a decade. This has included ultra pure analytical standards for pharmacokinetic studies for compounds undergoing phase I, II, and III clinical studies. We specialize in assisting clients in the development of the most effective routes to prepare compounds and quotes are prepared for the client at no charge. For more information, or to initiate a quotation, please visit the contact link to connect with us.

02

Medicinal Chemistry

TSL has provided medicinal chemistry services as a contract research organization since 2001. Interactions can take place in a number of ways including full-time equivalent (FTE) including both Masters and PhD level scientists and combinations of the two. The company has help discover and develop a number of compounds into the clinic and carried preparations through from the milligram to the multi-hundred gram scale for advanced biological tests. For further details, please visit the contact link above to connect with us

03

Continuous Manufacturing

TSL has been actively assisting customers around the world in transferring legacy manufacturing methods to better and greener continuous mode of manufacturing since 2004. TSL developed a host of technologies in the field of continuous manufacturing and process analytical technologies critical for the improvement of the legacy batch methods. Some of these technologies are viewed as enabling in the field of continuous manufacturing and PAT. TSL is currently in the process of forming a new division for bringing these core technologies as PnP solutions for PAT and RTRT. Stay tuned for the annoucement.

PEPPSI CATALYSTS

The PEPPSI family of catalysts, sold globally by TSL, is a proprietary catalyst system of TSL. Following pre-catalysts are available from TSL. Please contact us for details.

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